Imperfect impact

The problems with impact factors are well known – I could give you a long list of things to read that explain why, but just start with this blog post from Stephen Curry and go from there.

I have a slide that I use in my talks that sums up one particular problem – that the impact factor (IF) of any given journal tells you absolutely nothing about any given article in that journal. For example, the current IF of Organometallics is just over 4, whereas Nature‘s is more than 10 times that at just over 41. But does that mean that every Nature paper is 10 times ‘better’ than every Organometallics paper? (Answer: of course not! – and how on Earth would you measure ‘better’ anyway?). It also doesn’t guarantee that a particular Nature paper will have received more citations than any given Organometallics paper (after all, a wide distribution of citations make up an IF). Considering the perverse incentives in science, however, I wonder how many people would rather have on their CV an Organometallics paper that has received 50 citations in a year instead of a Nature paper that has garnered only 10 in the same period of time?

Anyway, I digress. The slide I have looks at things from a different point of view. Wouldn’t it be interesting if you could take exactly the same paper and publish it at roughly the same time in a bunch of different journals? Take your fancy-metal-catalyzed-cross-coupling-based synthesis of tenurepleaseamycin and submit it to (and have it published in) Angewandte, JACS, Nature Chem, Science, JOC, Tet Lett and Doklady Chemistry and then sit back and see how the citations roll in. Of course, it’s the same paper – it’s not a better paper in one journal than another, so it will get cited roughly equally in all journals, right? Well, all you can really do is speculate, because if you did try to do exactly that you’d end up really annoying some chemistry-journal editors and you might not get the paper published anywhere (well, I can think of a few places that would probably still take it, but discretion is the better part of valour and all that).

Well, never fear! The experiment has been done. Although it wasn’t an experiment, it wasn’t done for the purpose of comparing citations in different journals and it’s happened more than once. It turns out that in medical publishing, editorials/white papers occasionally get published in more than one journal. So, say hello to ‘Clinical Trial Registration — Looking Back and Moving Ahead‘. A few years back, I looked at the citations this paper had received in a range of different journals and the IFs of those journals – the slide from my talk with all of the data on is shown below.


There’s a pretty good correlation between the number of citations that this identical paper received in each journal with the IFs of those journals. Of course, perhaps more people read the New England Journal of Medicine than the Medical Journal of Australia and so a wider audience will likely mean a wider potential-citation pool. Whatever the reasons (and it’s not all that difficult to come up with others), the slide shows how silly it is to assume that the IF of a journal has any bearing on how good any particular paper in that journal is. As I have said before, the only way to figure out if a paper is any good is to actually read the damn thing – the name (or IF) of the journal in which a paper is published should never act as a proxy for how awesome (or not) a paper is.

So, as well as pointing out one specific flaw in the IF, when showing this slide it does allow me to make a joke about how the correlation would be even better if it wasn’t for some (imaginary, I hasten to add) Croatian citation ring… I apologize if I have offended any Croatian doctors who happen to be reading this… but the joke usually gets a laugh.

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Chemistry journal citation distributions

Over at my day job, I recently looked at the distribution of citations that 2012 and 2013 Nature Chemistry papers (Articles, Reviews and Perspectives) received in 2014 – essentially the citations that are used to calculate the 2014 impact factor of the journal. I would recommend having a read of that post before ploughing through this one. I’ve now done the analysis for five other general chemistry journals, just to see how they all stack up. In each case, the data is from Web of Science (All Databases) and is refined by document types ‘Article’ and ‘Review’. In the Sceptical Chymist post I also did the calculation for Nature Chemistry after removing the Review articles from the data, but haven’t done that here.

So, here is what Nature Chemistry looks like:


And here’s JACS, Angewandte Chemie (the International Edition), Chemical Science, Chem Comm and Chem Eur J (note that because of the wildly different volume of content across the 6 journals, the scale on the y-axis changes quite significantly – as does the smoothness of the distribution; also, for the Chem Comm and Chem Eur J, I have included magnified sections of the later portions of the distributions):






One way that you can compare journals that publish vastly different numbers of papers is to look at the percentage of published items that have more than a given number of citations. For example, each journal has 100% of papers with 0 or more citations, but what does the percentage drop to when you consider papers with 1 or more citations? If 5% of a journal’s papers have 0 citations in 2014, then the second point plotted on the graph would appear at 95% (i.e., 95% of papers would have one or more citation). If you do this analysis for the 6 journals above, this is what you find:

n or more cites all

If you stack these graphs on top of one another, you can then compare (for the most part) across the 6 journals:

n or more cites overlap

It’s interesting to note that JACS compares favourably to Angewandte, even though Angewandte publishes far more review-type articles, and also note how Chemical Science is not all that far behind Angewandte when you do this sort of analysis.

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Back to the future (of chemistry publishing)

So, here’s my obligatory Back-to-the-Future Day post and, because it is me doing this, it’s obviously about chemistry publishing. I figured I’d compare one issue of a journal published in 1985, with an issue published in 2015. Because the last time I looked at chemistry publications over a particular period of time I chose JACS, I thought I’d do Angewandte Chemie (the English edition) this time so that my friends over at Wiley don’t feel all left out. So, I looked at the October issue from 1985 (yes folks, there was only one issue of Angewandte each month in those prehistoric times) and compared it with the October 26th issue from 2015 (which is 5 days from now – and that seems appropriate considering the time-travel inspired nature of this post).

I just looked at the ‘Communications’ section of the issue in each case (that’s 27 papers from the 1985 issue and 51 papers from the 2015 issue) and this is what I found from these – admittedly tiny – samples:

1. Papers now have more authors on them than 30 years ago. The average (mean) for a paper in the 1985 issue was 3.07 authors, whereas it is more than double that in the 2015 issue at 6.37 authors per paper (the medians are 3 and 6, respectively).

2. Papers are now longer than they were 30 years ago. The average page extent for a paper in the 1985 issue was 2.15 pages, whereas it is now more than double that in the 2015 issue at 4.86 pages per paper (that’s just based on page ranges; not full printed pages in the journal). For comparison, the medians are 2 and 5, respectively.

***UPDATE – see comment below from @fluorogrol and my replies***

3. The geographical spread of corresponding authors is much greater now than it was 30 years ago. In 1985, German authors dominated Angewandte Chemie, but that’s not true anymore it seems – just look at the charts below.

Breakdown of geographical location of corresponding authors in Angewandte Chemie.

Breakdown of geographical location of corresponding authors in Angewandte Chemie.

As I mentioned above, these are really small samples so do take the analysis with a pinch of salt. That said, @fxcoudert has looked at these trends in more depth in the past and I highly recommend that you go and check out these two blog posts here and here.

I don’t know if this counts as #OldTimeChem or #FutureTimeChem (or perhaps a bit of both), but anyway, this is my little bit for #RealTimeChem week 2015!

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All your base are belong to JACS

This is a follow-up post to yesterday’s that looked at word clouds made up from the titles of JACS papers from the last 115 years.

Jake Yeston commented on Twitter about the lack of catalysis-based words in the clouds. This is something that also caught my eye and I’ve now had a chance to dig a little deeper into this.

The way the word clouds work (the ones you can make using Wordle at any rate) is by counting exact copies of the same word and then scaling the size of the word in the cloud in proportion to the number of times it appears in the input text. So, if you look closely at the word clouds from yesterday’s post, you will see ‘reaction’ and ‘reactions’ both appearing in the same word cloud. Similarly, acid and acids, complex and complexes, study and studies, and so on. Wordle also does not separate hyphenated words, so you will see things like ‘gas-phase’ and ‘electron-transfer’.

What does this mean for catalysis? Well, I started looking through the titles for the 2010-2014 data and found all of the following words (and there are probably other variants that I missed):

anticatalysis, autocatalysis, autocatalytic, biocatalysts, biocatalytic, catalase, catalysis, catalyst, catalytic, catalytically, catalyze, catalyzed, catalyzes, catalyzing, cocatalysis, cocatalytic, cocatalyzed, electrocatalysis, electrocatalyst, electrocatalysts, electrocatalytic, electrocatalyze, multicatalytic, nanocatalysts, organocatalysts, organocatalytic, photocatalysis, photocatalyst, photocatalysts, photocatalytic, precatalyst

This means that catalysis is being spread quite thin and not being lumped together as a single entry in the word clouds. But it gets worse. In the 2010-2014 cloud, if you look carefully you can find ‘palladium-catalyzed’… and remember what I said above about Wordle not separating hyphenated words? Not only is ‘palladium-catalyzed’ counted separately from ‘palladium’ and ‘catalyzed’, but also separately from things like ‘Pd-catalyzed’ too. And obviously you get lots of different ‘X-catalyzed’ terms, such as ‘gold-catalyzed’, ‘Rh-catalyzed’, ‘copper-catalyzed’, and so on. There’s an awful lot of catalysis going on, it just isn’t adequately captured in the word clouds. On the other hand, consider the word ‘synthesis’ — sure, it might lose some of its count to ‘synthetic’, but that’s about it; there aren’t anywhere near as many derivatives of ‘synthesis’ as there are of ‘catalysis’.

To get a sense of how much catalysis (in any and all of its guises) has been published in JACS down the years, I went back to the lists of titles and then searched for ‘catal’ as a fragment. For comparison, I did the same for ‘synth’ and what I found is plotted below.


In the 2000s, ‘catal’ words were almost level with ‘synth’ words, and by the end of the current decade, it looks very much like they will be in the lead. Is this the decline of synthesis?

Now, as I pointed out in yesterday’s post, it seems as though chemists really have something for acid and acids. Those words dominate the clouds in the early-to-mid part of the 20th century. On Twitter, Cafer Yavuz suggested that ‘base’ and ‘basic’ might be excluded as part of the set of common words, but I don’t think that is the case. Wanting to get a sense of acid vs base, I repeated the ‘catal’/’synth’ analysis for these words. The results are plotted below:


The analysis is not perfect, partly because ‘base’ and ‘basic’ can have different meanings (more so than acid and acidic), and ‘base’ is also a fragment of ‘based’ which might be adding to its total. Nevertheless, something interesting appears to be happening. When it comes to acids and bases, it seems that the balance of power (in JACS at least) is shifting — where acids once ruled supreme, bases took the crown in the 2000s and seem to be consolidating their position in the current decade.

If you have any questions about the analysis (or other things you want me to look for in the titles), just leave a comment or drop me a line on Twitter. Similarly, if you want the raw data, drop me a line by e-mail, I’m happy to share.

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115 years of JACS titles

When Nature Chemistry celebrated its 5th anniversary last year, we put together a word cloud (using Wordle) featuring the 150 words that appeared most often in the titles of the papers we had published up to that point. That was a collection of just under 600 papers, but a clear winner did emerge — ‘synthesis’ was the word used in titles more than any other (excluding some common words such as ‘from’, ‘by’, ‘to’, ‘with’, ‘and’, ‘so’, ‘on’…). It seems that a large part of chemistry is still very much about making things, and that reminds me of one of my favourite chemistry quotes:

‘la chimie crée son objet’ (chemistry creates its object) — Marcellin Berthelot, 1860.

The Nature Chemistry title-word cloud was not based on a particularly large data set, however, and is also from a very recent period. I wondered if the titles of chemistry papers have changed much over time, and so I decided to look to a journal with a lot more history. I wanted it to be a general chemistry journal to ensure there was no intrinsic bias towards words associated with a particular sub-field within chemistry and so I turned to the Journal of the American Chemical Society (JACS).

The date range I chose is somewhat arbitrary, but round numbers have a certain appeal and so I started at 1900 and worked my way up to 2014, the most recent complete year of JACS papers. This amounted to a little over 168,000 article titles and just shy of 2,000,000 words in total. I may well do more analysis in time, but first of all I decided to break down the data into decades (including a half-decade of 2010-2014 to cover the most recent papers) and look at the most popular 150 words for titles in each given period (excluding the same common words as we did when analysing the titles of Nature Chemistry papers).

Note that the size of each word corresponds to the number of times it appears in titles in that period — the larger it is, the more it is used. I have not combined words with the same root and nor have I combined singular and plural versions of the same word. I have made everything lowercase for the sake of simplicity though (otherwise ‘Synthesis’ appears as a separate entry to ‘synthesis’). Also, the number of papers published varies a lot between decades, so comparing the sizes of words between different clouds is meaningless.

This is what I found:



So, chemists at the start of the 20th century (yes, I know the century started on January 1st, 1901, but just go with it) were a determined bunch who liked to study milk, oil, wheat, sugar and urine — perhaps not all at the same time. Also, note the presence of a decent-sized ‘sulphur’. Yes, sulphur, with a ‘ph’. And remember, this is JACS, with all its American-ness. There’s not a hint of a ‘sulf’ to be found in JACS titles in this decade!



Still a healthy dose of determination, but also a lot of acid. And now ‘sulphur’ has become ‘sulfur’ — in fact, there are 143 ‘sulf’-based words and only 17 ‘sulph’ ones in titles from this decade.



Acid still looms large, but a lot of derivatives and compounds now too. Note that there is a lot more preparation than there is synthesis.



Seriously, what is it with chemists and acid? Compounds and derivatives remain popular and it seems as though synthesis is catching up a little with preparation.



The age of synthesis is upon us. And note the appearance of the word ‘spectra’ too. Also, ‘esters’, what’s going on there?



Synthesis remains dominant, but words such as ‘kinetics’ and ‘mechanism’ are growing larger, suggesting that there is an increasing drive to understand reactions as well. And ‘stereochemistry’ rears its head in the cloud for the first time.



Synthesis is not quite as prominent in the 1960s, but still a popular word in the titles of JACS papers. A new (and quite prominent) entry is ‘resonance’, along with ‘magnetic’, and note that both ‘nuclear’ and ‘proton’ are there too, reflecting the growing use of NMR as a technique to characterize chemical compounds. Another notable entry: ‘carbonium’ (the old name for carbocations), which was an active area of research at this time.



Chemists’ fascination with acid finally seems to be wearing off somewhat. And ‘complexes’ is now much more prominent. I suspect that this is a result of host–guest chemistry really taking off in the 1970s and the word ‘complex’ being associated with many more things than just traditional metal-coordination compounds.



There’s a fairly sizeable entry for ‘total’, and the vast majority of time it is used in the context of ‘total synthesis’ — and ‘synthesis’ itself dominates once more. Also note that the popularity of the word ‘via’ is increasing and both ‘novel’ and ‘new’ are well used (‘new’ seems to be a fairly constant presence in titles throughout the decades).



There’s still an awful lot of synthesis going on.



Nanotubes and nanoparticles make an appearance in the top 150 for the first time — nano comes of age? Other notable first-time entries (although small) are ‘supramolecular’, ‘self-assembly’ and ‘quantum’; I’m a little surprised it took so long.



Synthesis remains at the top, but look at the topics creeping into the top 150. ‘Metal–organic’ and ‘framework’ heralds the growing popularity of MOFs and it’s easy to miss, but there is also a little innocuous ‘graphene’ creeping into the picture at the bottom. ‘C–H’ is growing in size too, which is usually found in titles in the context of C–H activation. And finally, chemists’ love of ‘via’ is sealed!

To summarize, here are the top-ten words for each period:


(EDIT added June 3rd: I forgot to mention when I first posted this that for the top-ten lists I did combine simple singular and plural versions of the same word, so ‘reaction’ is actually ‘reaction’ and ‘reactions’ combined. Same goes for study/studies, complex/complexes, acid/acids and some of the others. What I did not do, however, is go beyond that and combine words that share the same root, so ‘synthesis’ and ‘synthetic’ have not been counted together and nor have ‘molecule’ and ‘molecular’, for example.)

Just to give you a sense of scale, if you don’t exclude the really common words, the top-20 words for the last full decade (2000-2009) are shown below (and remember that the words are scaled relative to the number of times they appear – the larger the word, the more times they appear in JACS titles).


So, the most common word in JACS titles is probably ‘of’ or, more meaningfully, ‘synthesis’.

(EDIT added June 3rd: there’s now a follow-up post, with some cautionary notes about word clouds and how they can miss some concepts…)

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The ups and downs of cyclohexane

Cyclohexane is undoubtedly an iconic molecule. Many of us learned to draw it (with varying degrees of proficiency) very early on in our organic chemistry classes as we were introduced to chairs, boats, half-chairs, twist-boats, cis, trans, A-values, conformation and, of course, axial and equatorial. Cyclohexane has six equatorial C–H bonds around the circumference of the ring and six axial C–H bonds, three pointing up and three pointing down.

It wasn't always axial (red) and equatorial (blue), you know...

A cyclohexane chair – it wasn’t always axial (red) and equatorial (blue), you know…

It turns out that it wasn’t always ‘axial’ and ‘equatorial’ though… and I only discovered this last week when I came across a 1953 letter-to-the-editor in Nature (Nomenclature of cyclohexane bonds) from Barton, Hassel, Pitzer & Prelog.

The letter notes (shown below) that the labels first suggested for the different C–H bonds on the cyclohexane ring were ɛ (epsilon) for what we now call axial, and χ (chi) for what we refer to as equatorial these days:


The citation (the subscript ‘2’ in the excerpt above) is to a paper by Odd Hassel published in 1943 in something called Tidsskr. Kjemi, Bergv. Met. which turns out to be the Norwegian journal Tidsskrift For Kjemi Bergvesen og Metallurgi (I’m sure that’s cleared it up for you…). Even if my Norwegian was up to scratch (it isn’t), I thought it would be somewhat tricky to track down a copy of this article to find out the reasoning behind the choice of those particular descriptors.

Fortunately, the article was later translated into English and published in Topics in Stereochemistry in 1971, along with an article by Derek Barton that had originally been published in 1950 in the journal Experientia.

Hassel’s paper — The cyclohexane problem — explains the origin of the descriptors as follows:


For those of you paying attention, you may have noticed a problem. Whereas the Nature paper refers to ɛ and χ, the original Hassel paper refers to ɛ and κ (kappa). And based on the Greek origins of the descriptors, it is clear that it should be κ and not χ. Go back and look at the excerpt from the Nature paper above — even squinting a bit, it would need to be a very charitable interpretation to say that the symbol in question is κ and not χ. It seems that something went awry in the publication process (a couple of book chapters also confirm that the original descriptors were ɛ and κ).

One of these book chapters also pointed me in the direction of a 1954 Science paper, which shared the same authors (Barton, Hassel, Pitzer and Prelog) — and the same title — as the earlier 1953 Nature paper. On closer inspection, the letter in Science is, with one important exception, exactly the same as the one that appeared in Nature. See if you can spot the difference in this excerpt from the Science paper:


So, Science got it right; a kappa (κ) and not a chi (χ) for the equatorial bonds. Perhaps more remarkable, however, is that both Science and Nature published the *same* letter (the Nature letter was published on Dec 12, 1953 and the one in Science on Jan 1, 1954) — I wonder whether the editors knew of the dual publication…?. Anyway, what was the ultimate purpose of this letter, this letter that was deemed so important that it should be published in both Science and Nature? Well, it was essentially just a proposal of new nomenclature for the different C–H bonds in cyclohexane.

After noting that the epsilon/kappa descriptors were difficult to remember, the authors pointed out that alternative nomenclature had been suggested by Beckett, Pitzer and Spitzer in a 1947 JACS paper. Basing their terms on geography rather than Greek, they had suggested the now-familiar ‘equatorial’ (e) for the C–H bonds around the equator of the ring and ‘polar’ (p) for the C–H bonds pointing either north or south away from the mean plane of the ring.

As highlighted in the Barton/Hassel/Pitzer/Prelog letter, however, the word ‘polar’ has another — very different — meaning in chemistry, and in an effort to prevent any confusion, they suggested that instead of polar, a better term would be ‘axial’. In another twist, the proposal to use ‘axial’ was actually made by Christopher Ingold who, despite this contribution, is only acknowledged in the Nature/Science letter (see below), rather than sharing in the authorship.

concluding para

Considering that ‘equatorial’ was already suggested in the earlier Beckett, Pitzer and Spitzer JACS paper and ‘axial’ is Ingold’s idea, the role of Barton, Hassel and Prelog appears to be one of making an authoritative plea (with Pitzer) to the community for a new standard to be adopted, rather than defining the new nomenclature themselves.

UPDATE 11/05/2015 – here’s an interesting post about Hermann Sachse and his attempts to get his ideas about the conformation of cyclohexane across to the wider chemistry community towards the end of the 19th century.

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A silicon spoof

This post is a follow-up to yesterday’s (did you notice the date?) that looked at an April 1981 paper by Dietmar Seyferth and James J. Pudvin published in the (now defunct) ACS journal CHEMTECH. This article reports the isolation of vacant 3d orbitals when tetramethylsilane is pyrolysed at temperatures in excess of 2,000 °C. Although a spoof, the paper is written so well, and with such attention to detail (the authors even include the supplier name and catalogue number for the ultrapure silicon tetrachloride that they supposedly used in their experiments), that the joke is not immediately obvious.

As I said yesterday, I’d never heard of the paper until Scott Denmark told me about it — and he was also the one who kindly provided me a copy (I doubt even #icanhazpdf would have worked for this one). I’ve had it sitting as an e-mail attachment for quite a while, but I figured the time had come to write about it — and looking at the calendar yesterday, I couldn’t resist. When putting the post together, however, I figured I would do a little more digging and see what else I could find out related to the article, and this post is the result.

Dietmar Seyferth

Although there are two authors listed on the paper, only one of them is real — and that’s Seyferth. Seyferth was the founding Editor-in-Chief of the ACS journal Organometallics and served in that position from the very first issue in January 1982 until 2010. In 2010, a special issue of Organometallics was published in honour of Seyferth (the Seyferth Festschrift) which featured an autobiographical essay entitled, ‘Looking Back on Happy Years in Chemistry‘. This 34-page article is remarkable in many ways, not least because the last 27 pages contain Seyferth’s detailed curriculum vitae (including full publication list)!

There are some interesting stories in the first 7 pages, however, not least the one about the Seyferth template (which ‘sold well for a number of years but ultimately was done in by ChemDraw’), but also one describing the story behind the CHEMTECH paper I blogged about yesterday — I reproduce that passage here:

Not all of my writings have been serious in nature. No. 353 in my publication list has the innocuous title “The Generation of a Highly Reactive Intermediate in the High-Temperature Pyrolysis of Tetramethylsilane” but really is a spoof in which I, with a fictitious coauthor, J. J. Pudvin, report the isolation and reactions of pure silicon 3d orbitals. I presented this orally at an organosilicon conference at Iowa State University in 1975 to the great amusement of my audience. Then there also is the only partly published (anonymously, without my knowledge, in CHEMTECH) “Researchmanship, Or How to Get Your Ph.D. Without Actually Working”, written in my younger years and modeled on Stephen Potter’s Gamesmanship, Lifesmanship, and One-upmanship books which were very popular at Harvard in the 1950s. Here J. J. Pudvin made his first appearance.

Using my highly advanced Internet-searching techniques (OK, I Googled it), I managed to find what claims to be the text of that other piece in which Pudvin first sprang into existence — it’s well worth a read too. Other anecdotes about Seyferth can be found on this webpage that lists the faculty members in the department of chemistry at MIT during the time that the class of 1964 were there. I particularly like this one:

When one of the new scholars asked him [Seyferth] how long it took a student to complete a Ph.D. in his research group, the answer was “The bad students — three years; the good ones — five.”

Anyway, back to the CHEMTECH paper and those 3d orbitals. Checking on Web of Science, the paper has apparently been cited just the once, but I’m not sure if the authors citing it are aware of just what they are citing… here’s the relevant passage in the citing paper (the bit in red is the reference to the CHEMTECH article).

A citation to a paper that suggests it is possible to isolate d orbitals...

A citation to a paper that suggests it is possible to isolate d orbitals…

There’s also a mention of Seyferth’s paper in the book Organic Chemistry: The Name Game: Modern Coined Terms and Their Origins in the context of other spoof chemistry articles (most of which are in German it turns out). By the power of Greyskull Google Books, you should be able find large chunks of the book here.


Another interesting part of putting together yesterday’s post was learning about CHEMTECH, an ACS publication that I had never heard of before being told about the Seyferth paper. It was launched in 1971 and ceased to be in 2001 (the last issue of CHEMTECH was actually published in December of 1999, but it re-emerged in 2000 as Chemical Innovation — although that only lasted until December 2001). The editorial in the last-ever issue spells out the reason for its demise:

If you are a subscriber or a reader of the ACS news department in Chemical & Engineering News, you already know that CI is closing shop. In these times of slow economy and greater attention to the bottom line, it was almost inevitable. Even the redesign and renaming of this magazine 2 years ago couldn’t reverse the decline in subscriptions, especially the institutional subscriptions that are necessary to keep a magazine like this afloat. So we take our leave. In the spirit of Rodgers and Hammerstein, I can say that all of my memories are happy tonight.

I beg your pardon.

I beg your pardon.

As with the launch of many new chemistry publications, the arrival of CHEMTECH (or Chemical Technology as was its official title back then) was heralded in the pages of Chemical & Engineering News. I’m sure that the ‘technology of urea’ and ‘the R&D and manufacturing of mothproofing substances’ would prove to be fascinating, but something else included in the description of what this new publication was going to cover was something that you wouldn’t (and shouldn’t) see today (that said, it wasn’t appropriate back in 1971 either). Just in case you were wondering, I’ve highlighted in yellow the offending bit in the passage I’ve grabbed from the pdf… yikes.

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